Scientist II - Process Development

Responsibilities:

• Design, execute, oversee, and interpret experiments in partnership with other team members.
• Independently draft, review, and finalize both technical protocols and scientific reports while interacting in a cross- specialty environment.
• Help determine process parameters range for cell culture and downstream processing to optimize PSC starting material yield and quality in a bioreactor system.
• Identify important process parameters and implement appropriate analytics.
• Maintain and culture PSCs utilized as starting material for downstream differentiation. This includes regular weekend/holiday in-lab activities.
• Assess gaps in PSC maintenance and growth conditions for banking, including platform evaluation, GMP-readiness and scale up efforts.
• Collaborate, cross-functionally, to solve scientific problems outside of function.
• Coordinate with platform and research teams as well as other Tech Ops groups to prioritize and plan characterization and distribution of cell materials.
• Participate in tech transfer activities to Manufacturing.
• Analyze and document experimental data in electronic laboratory notebooks in a timely and accurate manner.
• Prepare and follow standard operating procedures, batch records, reports, and other process documentation.
• Mentor and motivate others in scientific and/or technical topics with the goal of enabling key activities to be completed appropriately and on-time.
• Organize and present scientific data to peers at internal platforms.

Minimum Requirements:

• Ph.D or MSc. degree in a Biological Science, such as Biochemistry, Immunology, Molecular Biology, or similar
• Ph.D 2+ years of experience or MSc. 10+ years of experience, preferably in an industry setting
• Extensive mammalian cell culture and cell characterization experience, ideally with PSCs
• Practical knowledge of experimental design (e.g., DoE) software and statistical analysis of data
• Understanding and experience of molecular techniques such as cell imaging, flow cytometry, or qPCR and ddPCR is desired.
• Ideally experience with Bioreactor cell culture and bioprocessing.
• Ability to plan experiments and independently execute complex tasks.
• Strong English written and verbal communications skills.
• Proficiency in technical scientific writing.
• Ability to work in a fast-changing environment.
• Collaborative team player